The composition and condition of membrane lipids, the morphology of erythrocytes, and hemoglobin distribution were explored\nwith the help of laser interference microscopy (LIM) and Raman spectroscopy. It is shown that patients with cardiovascular diseases\n(CVD) have significant changes in the composition of their phospholipids and the fatty acids of membrane lipids. Furthermore,\nthe microviscosity of the membranes and morphology of the erythrocytes are altered causing disordered oxygen transport by\nhemoglobin. Basic therapy carried out with the use of antiaggregants, statins, antianginals, beta-blockers, and calcium antagonists\ndoes not help to recover the morphofunctional properties of erythrocytes. Based on the results the authors assume that, for the relief\nof the ischemic crisis and further therapeutic treatment, it is necessary to include, in addition to cardiovascular disease medicines,\nmedication that increases the ability of erythrocytes� hemoglobin to transport oxygen to the tissues. We assume that the use of\nLIM and Raman spectroscopy is advisable for early diagnosis of changes in the structure and functional state of erythrocytes when\ncardiovascular diseases develop.
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